With more than 40,000 women diagnosed with breast cancer and 180,000 men diagnosed with prostate cancer, cannabis treatment can decrease the size and effects of the tumor, while making conventional treatment even more efficient. Cancer doesn’t solely express itself with tumor growth. Other symptoms like nausea, anxiety, and pain can also be treated with cannabis.
Patients with late diagnoses have seen remission by treating their cancer with THC and CBD oil along with a proper nutrition. In a purified and organic form, these cannabinoids can attach to cancerous cells and switch off their ability to grow.
CBDA Reduces Tumor Size and Growth
Cannabidiolic Acid (CBDA) is the acidic version of CBD. This potent cannabinoid inhibits MDA-MB-231 breast cancer cells. CBD, the non-psychoactive compound in cannabis, has anti-proliferative effects that prevent tumor cells from replicating and growing. In essence, CBD inactivates the DNA that leads to a variety of cancers.
Studies have shown that cannabis can help many breast cancer patients, especially those that have HER2-positive breast cancer and triple-negative breast cancer, one of the toughest types of breast cancers to treat. In 2010, a team of Spanish researchers published a study in the journal of Molecular Cancer. They found that THC and CBD (found in cannabis) interact with CB2 cell receptors, the same receptors used to drive tumor growth.
THC and CBD both inhibit cancer growth and reduce the size of the tumor. A January 2015 study in Molecular Oncology published a similar study to show the effectiveness of CBD on triple-negative breast cancer patients. CBD inhibited epidermal growth factor along with reducing growth and inflammation.
Cannabinoids Induce Cell Death in Cancer Cells
When administered with THC, prostate cancer cells begin to die. Prostate cancer cells have more CB1 and CB2 cell receptors than in normal cells. Cannabinoids increase enzymes that help activate programmed cell death and decrease proteins that prevent these deaths. Additionally, cannabis can reduce androgen, a male sex hormone that helps prostate cells grow. Androgen deprivation therapy is currently a common treatment for prostate cancer.
In the British Journal of Cancer a study was published showing that THC in patients with bone metastatic prostate cancer made these cancer cells die off. Additionally, CBD prevented these cancerous cells from surviving through a form of self-destruction. CBD has no negative toxic effects compared to contemporary chemotherapy treatments and can still be an effective way of treating aggressive cancers like prostate and breast cancer.
Many patients have seen significant improvement in their condition using cannabis, including the world-renowned Rick Simpson oil. Concentrated forms of cannabis can help inhibit gene expression which helps cancerous cells from replicating.